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18. Cisco Systems
Fortune 500 rank: 71
2007 profit: $7.33 billion

Cisco had the right stuff in 2007. Profit shot up 31% on a 23% sales increase.

The networking equipment giant benefited in large part from Internet service providers who upgraded their systems to meet new bandwidth demand from videos and other applications.

Cisco saw the most growth in emerging markets like Africa and Eastern Europe as U.S. companies slowed their network building.

NEXT: Hewlett-Packard

Last updated April 24 2008: 11:07 AM ET