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12. Corning
Fortune 500 rank: 417
Corning raked in 90% of its $2.2 billion in profits last year -- a 16% rise -- from supplying LCD glass for TV and computer screens. The company is now betting on its latest novel technology: emission filters for diesel cars and trucks.

NEXT: 13. Applied Materials
Last updated April 24 2008: 11:04 AM ET