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9. Qualcomm
Fortune 500 rank: 297
Earnings were up 34% to $3.3 billion, bolstered by strong demand for high-speed cellular networks. But Qualcomm, a supplier of cell phone chips, faces several challenges in 2008, including ongoing patent disputes and a slowdown in handset demand.

NEXT: 10. Dell
Last updated April 24 2008: 11:04 AM ET