3. Prometheus Research
3. Prometheus Research
2009 Revenues: $3.6 million
5-year Annual Growth Rate: 103%

Leon Rozenblit
Location: New Haven, CT
Year Founded: 2000

About the business:
Leon Rozenblit started Prometheus Research in grad school. What originated as a consulting business quickly evolved into a software program that helps scientists manage their data efficiently.

The projects soon grew too big for the technology they were using. The company needed to quickly reform their existing platform. Thanks to an angel investor, they received the funds they needed and created an even more efficient -- though more complex -- platform.

Prometheus Research is gearing up to expand its services beyond science world.

--By Ashley Bush and Mary Kay Leonard

The Initiative for a Competitive Inner City (ICIC) defines inner cities as core urban areas with higher unemployment and poverty rates and lower median incomes than their surrounding metropolitan statistical areas. For the 2011 list, ICIC received more than 2,000 solicited nominations using its database of small businesses and through the support of its nominating partners, including the U.S. Conference of Mayors, Staples, and the Small Business Administration. Companies were ranked by compound annual growth rate (CAGR) based on their revenue over the five-year period between 2005 and 2009 (the last year for which complete data was available).
Last updated May 18 2011: 5:14 PM ET